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Vapendavir diphosphate

CAS No. 1198151-75-5

Vapendavir diphosphate( —— )

Catalog No. M33162 CAS No. 1198151-75-5

Vapendavir diphosphate is a potent enteroviral capsid binder (CB) and has a potent antiviral activity for enterovirus 71 (EV71) replication (EC50: 0.5-1.4 μM in different EV71 strains).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Vapendavir diphosphate
  • Note
    Research use only, not for human use.
  • Brief Description
    Vapendavir diphosphate is a potent enteroviral capsid binder (CB) and has a potent antiviral activity for enterovirus 71 (EV71) replication (EC50: 0.5-1.4 μM in different EV71 strains).
  • Description
    Vapendavir diphosphate (BTA798 diphosphate) is a potent enteroviral capsid binder (CB). Vapendavir diphosphate (BTA798 diphosphate) possesses potent antiviral activity for enterovirus 71 (EV71) replication, with EC50 values of 0.5-1.4 μM in different EV71 strains.
  • In Vitro
    Vapendavir (BTA798) efficiently inhibit the in vitro replication of 21 EV71 strains/isolates that are representative of the different genogroups A, B, and C.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1198151-75-5
  • Formula Weight
    578.45
  • Molecular Formula
    C21H32N4O11P2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 6.75 mg/mL (11.67 mM; Ultrasonic )
  • SMILES
    O=P(O)(O)O.CCOC1=NOC2=C1C=CC(OCCC(CC3)CCN3C4=NN=C(C)C=C4)=C2.O=P(O)(O)O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Tijsma A, et al. The capsid binder Vapendavir and the novel protease inhibitor SG85 inhibit enterovirus 71 replication. Antimicrob Agents Chemother. 2014 Nov;58(11):6990-2.?
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